{"title":"The presence of old Alus in GC-rich regions of the human genome - a genetic algorithm perspective","authors":"S. J. Anastasoff","doi":"10.1109/CEC.2002.1006201","DOIUrl":null,"url":null,"abstract":"More than 10% of the human genome is comprised of a sequence known as an Alu repeat, with over a million copies of this distributed throughout our DNA. Detailed analysis of the distribution of this sequence shows it to be dispersed in an unusual way. In the work presented here, a genetic algorithm simulation was developed as the basis for modeling transposons (of which the Alu is one type). This simulation was used to explore the evolutionary conditions under which such a distribution could arise.","PeriodicalId":184547,"journal":{"name":"Proceedings of the 2002 Congress on Evolutionary Computation. CEC'02 (Cat. No.02TH8600)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2002-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 2002 Congress on Evolutionary Computation. CEC'02 (Cat. No.02TH8600)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CEC.2002.1006201","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
More than 10% of the human genome is comprised of a sequence known as an Alu repeat, with over a million copies of this distributed throughout our DNA. Detailed analysis of the distribution of this sequence shows it to be dispersed in an unusual way. In the work presented here, a genetic algorithm simulation was developed as the basis for modeling transposons (of which the Alu is one type). This simulation was used to explore the evolutionary conditions under which such a distribution could arise.
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