Cognitive Deficits in Cocaine Users

B. Saberi
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Abstract

Chronic cocaine use can result in neuropsychological performance deficits and brain metabolism and perfusion abnormalities. These problems can be reversed and improved during abstinence. Memory storage difficulties cause significant verbal learning efficacy impairment in chronic cocaine users. Cognitive flexibility, learning, memory, attention and reaction time impairment can be seen in chronic cocaine users. Wisconsin card sorting test shows a strong correlation between deteriorations of moderate executive performance and the chronicity of cocaine and other drugs use [1-3].
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可卡因使用者的认知缺陷
长期使用可卡因可导致神经心理功能障碍和脑代谢和灌注异常。这些问题可以在禁欲期间得到扭转和改善。记忆储存困难引起慢性可卡因使用者显著的语言学习效能障碍。在慢性可卡因使用者中可以看到认知灵活性、学习、记忆、注意力和反应时间障碍。威斯康星卡片分类测试显示,中度执行绩效的恶化与可卡因和其他药物使用的慢性性有很强的相关性[1-3]。
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