Tracking Promyelocytic Leukemia Nuclear Bodies for Disease Detection: A Proof of Concept via Filtering

J. Hailes, M. Kouritzin, R. Marsh, J. McCrosky
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Abstract

Nonlinear filtering has proven to be a valuable tool in many applications ranging from search and rescue to performing arts. Herein we discuss an application of filtering to medical imaging. A sample problem in detecting, tracking, and characterizing the movement of promyelocytic leukemia nuclear bodies within a cell nucleus is used to demonstrate the utility of nonlinear filtering in this area. Simulation results are presented and discussed.
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跟踪早幼粒细胞白血病核体用于疾病检测:通过过滤的概念验证
非线性滤波已被证明是一个有价值的工具,在许多应用范围从搜索和救援表演艺术。本文讨论了滤波在医学成像中的应用。在检测,跟踪和表征早幼粒细胞白血病核体在细胞核内的运动的一个样本问题被用来证明非线性滤波在这一领域的效用。给出了仿真结果并进行了讨论。
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