Neurotoxicity in the treatment of Parkinson's disease

Abstract

Currently, there is no neuroprotective therapy for the treatment of Parkinson's disease (PD), which would slow down the progression of the pathological process and prevent the development of the neurodegenerative process. The applied symptomatic therapy does not give a positive effect. In this paper, an overview of antiparkinsonian medications that are used in the treatment of PD is made. These drugs give side effects, causing neurotoxicity, while chemical agents, i.e. oxygen radicals have an adverse effect on the structure or function of the central or peripheral nervous system.