Crude ethanolic extract and fractions of buchholzia coriacea modifies salivary secretion and electrolyte compositions in rat

O. Odukanmi, A. Salami, M. Isa, S. Olaleye
{"title":"Crude ethanolic extract and fractions of buchholzia coriacea modifies salivary secretion and electrolyte compositions in rat","authors":"O. Odukanmi, A. Salami, M. Isa, S. Olaleye","doi":"10.5455/ajpbp.20190411102349","DOIUrl":null,"url":null,"abstract":"Background: Extract of Buchholzia coriacea (BC) has been reported for its potent antimalarial effect. Unlike certain established antimalarial drugs reported for their roles in modifying saliva flow and components, BC effect on saliva is unknown. The effect of BC on saliva flow and its components was investigated. \nMaterials and Methods: Thirty Male Wistar rats 150.7 ± 13.3 g were used for the study. They were grouped into six (n=5) and treated with the various component of BC extract for 2 weeks. Group 1 (control) received distilled water, groups 2-6 received 200 mg/kg of the oily portion of the extract, 100 mg/kg, 200 mg/kg of the crude extract, 200 mg/kg absolute ethanol and 200 mg/kg aqueous ethanol fractions of BC respectively. Body weight, salivary flow rate, electrolyte compositions and morphological changes were determined using standard methods. Values were expressed as Mean ± standard error of mean, compared, analysed and considered significant at p","PeriodicalId":146536,"journal":{"name":"American Journal of Physiology, Biochemistry and Pharmacology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Physiology, Biochemistry and Pharmacology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5455/ajpbp.20190411102349","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Extract of Buchholzia coriacea (BC) has been reported for its potent antimalarial effect. Unlike certain established antimalarial drugs reported for their roles in modifying saliva flow and components, BC effect on saliva is unknown. The effect of BC on saliva flow and its components was investigated. Materials and Methods: Thirty Male Wistar rats 150.7 ± 13.3 g were used for the study. They were grouped into six (n=5) and treated with the various component of BC extract for 2 weeks. Group 1 (control) received distilled water, groups 2-6 received 200 mg/kg of the oily portion of the extract, 100 mg/kg, 200 mg/kg of the crude extract, 200 mg/kg absolute ethanol and 200 mg/kg aqueous ethanol fractions of BC respectively. Body weight, salivary flow rate, electrolyte compositions and morphological changes were determined using standard methods. Values were expressed as Mean ± standard error of mean, compared, analysed and considered significant at p
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
茯苓粗乙醇提取物及组分对大鼠唾液分泌及电解质成分的影响
背景:鹿茸提取物(Buchholzia coriacea, BC)因其有效的抗疟作用而被报道。与某些已知的抗疟疾药物不同,它们的作用是改变唾液流动和成分,BC对唾液的影响尚不清楚。研究了BC对唾液流动及其成分的影响。材料与方法:选用150.7±13.3 g雄性Wistar大鼠30只。他们被分成6组(n=5),用BC提取物的不同成分治疗2周。组1(对照组)分别给予200 mg/kg油提取物、100 mg/kg粗提取物、200 mg/kg无水乙醇和200 mg/kg乙醇提取物。采用标准方法测定大鼠体重、唾液流速、电解质组成及形态学变化。值表示为平均值±平均值的标准误差,比较,分析并认为p显著
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats Self-reported Hormonal Changes-associated with Fried Potato Chip Consumption among Female University Students in Saudi Arabia, Makkah: A cross section Study Contribution of storage conditions of antibiotics in pharmacies on efficacy loss of Amoxicillin and Tetracycline against strains of Escherichia coli and Staphylococcus aureus in the city of Lome. Biochemical effects of ethanolic extract from root bark of Salacia nitida L. benth in Plasmoduim berghei-malaria infected mice. Comparison of rheumatoid factor of IgM, IgG and IgA isotypes with disease activity score 28 in patients of rheumatoid arthritis
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1