Point of care fiber optical sensor for non-invasive multi parameter monitoring of blood and human tissue biochemistry

Abstract

Compact fiber optical and thermal sensor for non invasive measurement of blood biochemistry including glucose, hemoglobin and it's derivatives concentrations is developed as a prototype of the point-of-care diagnostic devices for cardiologic, tumour and diabetic patients. Integrated platform for data acquisition, data processing and communication to remote networks has been developed on the pocket PC. Method of non-invasive monitoring of human blood biochemistry based on spatially localized NIR diffuse scattering spectroscopy and metabolic heat measurements has been developed. Multivariate statistical analysis and cluster analysis was applied to convert sensor pickup signals into physicochemical variables.