Mehtap Boduc, M. Roessler, R. Mandic, Christoph Netzer, C. Güldner, U. Walliczek-Dworschak, M. Mandapathil
{"title":"Presence and Quantity of COX-2 in Lymph Node Metastases of Patients with Head and Neck Cancer","authors":"Mehtap Boduc, M. Roessler, R. Mandic, Christoph Netzer, C. Güldner, U. Walliczek-Dworschak, M. Mandapathil","doi":"10.24983/SCITEMED.AOHNS.2017.00024","DOIUrl":null,"url":null,"abstract":"COX-2 expression in primary lesions, as well as lymph node metastases, appears to identify HNSCC patients at higher risk in all tumor sites. Adjuvant therapeutic approaches targeting COX-2 might be a promising tool in this patient population.","PeriodicalId":272593,"journal":{"name":"Archives of Otorhinolaryngology-Head & Neck Surgery","volume":"5 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Otorhinolaryngology-Head & Neck Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24983/SCITEMED.AOHNS.2017.00024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
COX-2 expression in primary lesions, as well as lymph node metastases, appears to identify HNSCC patients at higher risk in all tumor sites. Adjuvant therapeutic approaches targeting COX-2 might be a promising tool in this patient population.
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