Tratamento com andrógenos como possibilidade de melhoria do prognóstico reprodutivo em mulheres com envelhecimento ovariano

Abstract

Justification

The response to ovarian stimulation is a keyelement in assisted reproduction (AR). Despite recent advances in the techniques, patients with low ovarian reserve have poor prognosis and represent a challenge in reproductive medicine.

Objective

To propose a strategy to improve reproductive prognosis of women older than 38 years or young women with low antral follicle count, through the use of testosterone prior to ovarian stimulus.

Material and methods

Survey data from the scientific literature in the field of reproductive medicine.

Results and conclusions

The use of androgens in stages preceding ovarian stimulation in IVF cycles seems to be great tool for improving oocyte response inoocyte controlled stimulation of patients older than 38 years or with diminished ovarian reserve, improving both quantity and quality of oocytes and increasing rates of pregnancy and live‐born.