Influencing Factors Affecting Successful Organ Donation and Families' Consent to Donate after Drain Death

Eun Woo Lee, Hye-Yeon Jang, S. Han, K. Han, S. Oh, Young-Nam Roh
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引用次数: 3

Abstract

Background: This study was conducted to identify the factors influencing successful organ donation and families’ consent to donate after brain death. Methods: Medical records and data regarding organ donation counseling with the families of 107 brain-dead potential donors between September 2012 and March 2016 at a single tertiary medical center were retrospectively reviewed. Results: The final consent rate was 57.9% (62/107), and successful donation was performed in 40.2% (43/107) of cases. Univariate and multivariate analyses revealed that the independent factors associated with successful organ donation were age <60 years (odds ratio [OR], 3.384; 95% confidence interval [CI], 1.350 to 8.484; P=0.009), systolic blood pressure ≥90 mmHg (OR, 6.261; 95% CI, 1.418 to 27.653; P=0.015), and serum sodium level ≥150 mEq (OR, 4.215; 95% CI, 1.655 to 10.733; P=0.003). Family’s consent to donate was significantly associated with head trauma (OR, 3.538; 95% CI, 1.104 to 11.334; P=0.033) and serum sodium level ≥150 mEq (OR, 3.392; 95% CI, 1.404 to 8.194; P=0.007). Conclusions: Successful organ donation was associated with patient age, systolic blood pressure and serum sodium level. Family’s consent to donate was associated with head trauma and serum sodium level.
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影响器官捐献成功的因素及引流死亡后家属捐献意愿的因素
背景:本研究旨在探讨影响脑死亡后器官捐献成功与否及家属是否同意捐献器官的因素。方法:回顾性分析某三级医疗中心2012年9月至2016年3月107例脑死亡潜在供体患者家属的器官捐赠咨询记录和资料。结果:最终同意率为57.9%(62/107),成功捐赠率为40.2%(43/107)。单因素和多因素分析显示,与器官捐赠成功相关的独立因素是年龄<60岁(优势比[OR], 3.384;95%置信区间[CI], 1.350 ~ 8.484;P=0.009),收缩压≥90 mmHg (OR, 6.261;95% CI, 1.418 ~ 27.653;P=0.015),血清钠水平≥150meq (OR, 4.215;95% CI, 1.655 ~ 10.733;P = 0.003)。家属同意捐赠与头部创伤有显著相关性(OR, 3.538;95% CI, 1.104 ~ 11.334;P=0.033),血清钠水平≥150meq (OR, 3.392;95% CI, 1.404 ~ 8.194;P = 0.007)。结论:器官捐献成功与否与患者年龄、收缩压和血清钠水平有关。家属是否同意捐献与头部创伤和血清钠水平相关。
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