Anaplastic glioma diagnosis and its therapeutic significance

Abstract

Despite sufficient provision and active use of modern neuroimaging technologies, it is often too late to diagnose glioma. Clinical symptoms in anaplastic glioma appear within a period of 1-2 years and in glioblastoma - within less than a year. The use of new diagnostic equipment (multi-slice CT, high-angle MRI, and their varieties - MR spectroscopy, fMRI, diffusion tensor MRI, stereotactic diagnostics) allows identifying diseases that were previously detected only after autopsy. Despite the modern method of diagnosing a malignant brain tumor, its early diagnosis remains an urgent problem. At the same time, total removal of brain tumors is a difficult task for neurosurgeons. Thus, according to control CT and MRI of the brain, the radicality of resection reaches 40-50%. Practical application of modern neuroimaging technologies is being actively studied, but their use in HGG is still limited.