The influence of insufficiency of vitamin D on activity of endogenous antimicrobic peptides at children of early age with acute bacterial diseases of the respiratory system

Abstract

Determination of content of vitamin D and antimicrobic peptides (cathelicidin, β1defensins, lactoferrin and hBPI) in blood serum of 67 children with acute bacterial diseases of a respiratory system aged from 1 month up to 3 years taking into account the level of providing with vitamin D is carried out. The research showed that decrease in maintenance of a number of antimicrobial peptides in blood serum against the background of deficiency of vitamin D acts as risk factor of development of acute bacterial diseases of a respiratory system of children of early age.