The Relationship Between the Severity of Atherosclerosis and Periodontal Disease Index in Diabetic Patients

A. Güler, Emre Yılmaz, A. Demir, Neşe Bayıroğlu, A. Kalkan, F. Uzun, M. Ertürk
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Abstract

Introduction: Although the link between coronary artery disease (CAD) and periodontal disease has previously been demonstrated, there is insufficient research on how the severity of both diseases impact each other. This study aimed to investigate the relationship between the severity of periodontal disease and the diffuseness of CAD in diabetic patients. Patients and Methods: A total of 127 diabetic patients with CAD were included in this study. The SYNTAX score determined the diffuseness of CAD, and the patients were divided into two groups as the SYNTAX score ≤22 and >22. The plaque index and periodontal disease index were used in the dental evaluation. The relationship of these indexes to the diffuseness of coronary artery disease has been investigated. Results: In this study, the plaque index and periodontal disease index correlate significantly with the high SYNTAX score in diabetic patients. In univariate logistic regression analysis, PDI was a predictive variable for the SYNTAX score above 22 in diabetic patients. According to the ROC curve analysis, it was shown that the periodontal disease index of 4.3 could predict a high SYNTAX score. Conclusion: To sum up, we found a significant relationship between periodontal disease severity and coronary artery disease diffuseness. PDI was found to be a predictor of a high SYNTAX score.
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糖尿病患者动脉粥样硬化严重程度与牙周病指数的关系
导论:虽然冠状动脉疾病(CAD)和牙周病之间的联系已经被证实,但关于这两种疾病的严重程度如何相互影响的研究还不够。本研究旨在探讨糖尿病患者牙周病严重程度与冠心病弥漫性的关系。患者与方法:本研究共纳入127例合并冠心病的糖尿病患者。SYNTAX评分决定CAD的弥漫性,按照SYNTAX评分≤22分和>22分将患者分为两组。牙菌斑指数和牙周病指数用于牙齿评估。研究了这些指标与冠状动脉病变弥漫性的关系。结果:在本研究中,斑块指数和牙周病指数与糖尿病患者的高SYNTAX评分显著相关。在单变量logistic回归分析中,PDI是糖尿病患者SYNTAX评分在22分以上的预测变量。根据ROC曲线分析,牙周病指数为4.3可以预测较高的SYNTAX评分。结论:综上所述,我们发现牙周病严重程度与冠状动脉疾病弥漫性有显著关系。PDI被发现是高SYNTAX分数的预测因子。
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