Early and long-term results of endovascular treatment of cerebral aneurysms

V. Bobinov, L. Rozhchenko, A. Petrov, S. Goroshchenko, E. G. Kolomin, N. K. Samochernikh, N. Y. Tukanov, K. A. Samochernikh
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Abstract

Introduction. Postoperative angiographic examinations after endovascular treatment of cerebral aneurysms may demonstrate unstable results, both in the form of recurrence formation, and in the form of increased degree of occlusion with initially incomplete occlusion of the aneurysm sac. Cerebral aneurysm recurrences represent an important medical and social problem comparable in terms of hemorrhage risks with nonoperated aneurysms.Aim. To estimate the early and long‑term results of endovascular treatment of patients with cerebral aneurysms ope rated on using different endovascular techniques. Materials and methods. The present study included 167 patients (48 men and 119 women) with 195 cerebral aneurysms aged from 18 to 75 years who were operated on using endovascular techniques at the neurosurgical department No. 3 of the Russian Research Neurosurgical Institute named after Prof. A. L. Polenov from 2013 to 2016. The average age of the patients was 52 ± 12 years, the minimum age was 18 years, and the maximum age was 75 years. The choice of endovascular treatment method in the patients included in the study was based on anatomico‑topographic and morphometric features of aneurysm, as well as taking into account the period of aneurysmal disease course.Results. The study of data of control angiographic examinations after endovascular treatment of patients with cerebral aneurysms showed that in the remote postoperative period the degree of aneurysm occlusion may differ from that initially achieved. The probability of aneurysm recurrence after its isolated occlusion with coils may reach 13.1 % already in 6 months after surgical treatment, 31.7 % after 12 months and 22.3 % after 36 months, averaging 22.5 % (p < 0.05).Conclusion. The personalized approach in choosing optimal surgical tactics for the treatment of patients with cerebral aneurysms allows to achieve stable radical aneurysm occlusion, to decrease the incidence of postoperative complications and aneurysm recurrences in the long‑term postoperative period.
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脑动脉瘤血管内治疗的早期和长期效果
介绍。脑动脉瘤血管内治疗后的术后血管造影检查结果可能不稳定,既表现为复发形成,也表现为动脉瘤囊最初不完全闭塞,闭塞程度增加。脑动脉瘤复发是一个重要的医学和社会问题,其出血风险与未手术的动脉瘤相当。目的评价采用不同血管内技术治疗脑动脉瘤的早期和远期疗效。材料和方法。本研究纳入167例脑动脉瘤患者(男48例,女119例),年龄18 ~ 75岁,于2013 ~ 2016年在以A. L. Polenov教授命名的俄罗斯神经外科研究所第三神经外科采用血管内技术进行手术。患者平均年龄52±12岁,最小年龄18岁,最大年龄75岁。纳入研究的患者血管内治疗方法的选择是基于动脉瘤的解剖形态学和形态特征,并考虑动脉瘤病程的长短。对脑动脉瘤患者血管内治疗后对照血管造影检查资料的研究表明,在术后远段时间内,动脉瘤的闭塞程度可能与最初达到的程度不同。术后6个月孤立闭塞动脉瘤复发率为13.1%,12个月为31.7%,36个月为22.3%,平均为22.5% (p < 0.05)。在选择最佳手术策略治疗脑动脉瘤患者时,个性化的方法可以实现稳定的根治性动脉瘤闭塞,减少术后并发症的发生率和术后长期内动脉瘤的复发。
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