Molecular-biological and immunological properties of ribosomal vaccines.

Biomedical science Pub Date : 1991-01-01
L V Nikolaeva, E P Savel'ev
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Abstract

Data on the immunological properties and protective action of ribosomal vaccines are reviewed from the point of view of the structural and functional properties of ribosomes. Comparative analyses are presented for ribosomes from Gram-negative and Gram-positive microorganisms, and for ribosomes from prokaryotes and eukaryotes. Special consideration is given to the nature of the protective factors of ribosomal preparations and the mechanisms of ribosomal vaccine immunogenesis.

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核糖体疫苗的分子生物学和免疫学特性。
从核糖体的结构和功能特性的角度综述了核糖体疫苗的免疫学特性和保护作用。比较分析了来自革兰氏阴性和革兰氏阳性微生物的核糖体,以及来自原核生物和真核生物的核糖体。特别考虑核糖体制剂的保护因素的性质和核糖体疫苗免疫发生的机制。
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