Enhanced antibacterial activity of silver-doped chitosan nanofibers

TURKISH PHYSICAL SOCIETY 35TH INTERNATIONAL PHYSICS CONGRESS (TPS35) Pub Date : 2019-11-25 DOI:10.1063/1.5135401

N. C. Bezir, B. Bozkurt, A. Evcin, Burcu Özcan, Esengul Kır, G. Akarca, O. Ceylan

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引用次数: 2

Abstract

The production of nanofibers with specific properties by electrospinning has attracted significant attention for antibacterial applications. Electrospun nanofibers incorporated with antimicrobial silver agent have been synthesized with antimicrobial capability against S. aureus bacteria. Chitosan solution was prepared by dissolving chitosan in acetic acid following by stirring for 24 h at room temperature. Different amount of silver were added to chitosan solutions. The crystalline structure, thermal, morphologies and nanostructure properties of the sample are characterized by scanning electron microscopy (SEM), energy dispersive analysis of SEM-EDX and thermal gravimetry-differential scanning calorimeter (TG-DSC) respectively. Ag-doped chitosan nanofibers were successfully prepared by electrospinning. The antibacterial activity of Ag-doped chitosan nanofibers were examined on S.aureus bacteria.The production of nanofibers with specific properties by electrospinning has attracted significant attention for antibacterial applications. Electrospun nanofibers incorporated with antimicrobial silver agent have been synthesized with antimicrobial capability against S. aureus bacteria. Chitosan solution was prepared by dissolving chitosan in acetic acid following by stirring for 24 h at room temperature. Different amount of silver were added to chitosan solutions. The crystalline structure, thermal, morphologies and nanostructure properties of the sample are characterized by scanning electron microscopy (SEM), energy dispersive analysis of SEM-EDX and thermal gravimetry-differential scanning calorimeter (TG-DSC) respectively. Ag-doped chitosan nanofibers were successfully prepared by electrospinning. The antibacterial activity of Ag-doped chitosan nanofibers were examined on S.aureus bacteria.

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增强银掺杂壳聚糖纳米纤维的抗菌活性

静电纺丝法生产具有特殊性能的纳米纤维在抗菌方面的应用已引起人们的广泛关注。合成了含有抗菌银剂的静电纺丝纳米纤维，并对金黄色葡萄球菌具有抗菌作用。将壳聚糖溶解于醋酸中，室温搅拌24 h，制备壳聚糖溶液。在壳聚糖溶液中加入不同量的银。采用扫描电子显微镜(SEM)、SEM- edx能谱分析仪(SEM - edx)和热重-差示扫描量热仪(TG-DSC)分别表征了样品的晶体结构、热、形貌和纳米结构。采用静电纺丝法制备了银掺杂壳聚糖纳米纤维。研究了银掺杂壳聚糖纳米纤维对金黄色葡萄球菌的抑菌活性。静电纺丝法生产具有特殊性能的纳米纤维在抗菌方面的应用已引起人们的广泛关注。合成了含有抗菌银剂的静电纺丝纳米纤维，并对金黄色葡萄球菌具有抗菌作用。将壳聚糖溶解于醋酸中，室温搅拌24 h，制备壳聚糖溶液。在壳聚糖溶液中加入不同量的银。采用扫描电子显微镜(SEM)、SEM- edx能谱分析仪(SEM - edx)和热重-差示扫描量热仪(TG-DSC)分别表征了样品的晶体结构、热、形貌和纳米结构。采用静电纺丝法制备了银掺杂壳聚糖纳米纤维。研究了银掺杂壳聚糖纳米纤维对金黄色葡萄球菌的抑菌活性。

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TURKISH PHYSICAL SOCIETY 35TH INTERNATIONAL PHYSICS CONGRESS (TPS35)

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