A case of malignant melanoma presented with lombar vertebra fracture

A. Sarici, I. Kuku, İ. Berber, M. Erkurt, H. Ulubaba, S. Biçim, M. Durmuş, E. Kaya
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Abstract

Aims: Malignant melanoma is a type of skin cancer with a very poor prognosis. It is the most common skin cancer. Metastases are frequently observed in malignant melanoma, which can have a very aggressive course, even without skin findings. Here, we aimed to report a malignant melanoma case presenting with lumbar vertebra fracture, which is a unique form of presentation. Case description: A 31-year-old male patient was admitted to the internal medicine outpatient clinic with complaints of low back pain and inability to walk 15 days ago. After the first hour sedimentation value was found to be 101 in the examinations of the patient who came with the complaint of low back pain, he was referred to the hematology department with the preliminary diagnosis of multiple myeloma. Bone marrow aspiration and biopsy was performed. Non-hematopoietic cells were observed in bone marrow aspiration. L2 vertebra fracture was detected in lumbar MRI of the patient with bilateral limitation of movement in the lower extremities. The patient with L2 vertebral fracture was transferred to the neurosurgery service for operation. The patient was diagnosed with malignant melanoma after the frozen biopsy sent after the operation and the previous bone marrow biopsy. Conclusions: Bone marrow infiltration can be seen in malignant melanoma patients. However, a malignant melanoma patient presented with lombar vertebra fracture has not been reported before in the literature.
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恶性黑色素瘤伴腰椎骨折1例
目的:恶性黑色素瘤是一种预后很差的皮肤癌。这是最常见的皮肤癌。在恶性黑色素瘤中经常观察到转移,它可以具有非常积极的过程,即使没有皮肤发现。在这里,我们的目的是报告一个恶性黑色素瘤的情况下,腰椎骨折,这是一个独特的表现形式。病例描述:31岁男性患者,15天前来内科门诊就诊,主诉腰痛、不能行走。患者以腰痛为主诉,检查后发现第一个小时的沉降值为101,初步诊断为多发性骨髓瘤,转至血液科。行骨髓穿刺活检。骨髓抽吸观察到非造血细胞。在双侧下肢活动受限患者的腰椎MRI中发现L2椎体骨折。患者L2椎体骨折被转移到神经外科进行手术。经术后冰冻活检及既往骨髓活检诊断为恶性黑色素瘤。结论:恶性黑色素瘤患者可见骨髓浸润。然而,以腰椎骨折为表现的恶性黑色素瘤患者在文献中尚未见报道。
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