A case of multiple myeloma with unusual presentation

A. Momeni, Rooholah Masoomi
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Abstract

Extramedullary plasmacytoma is a rare and unusual complication of multiple myeloma (MM). Some sites for the extramedullary involvement of MM are the liver, spleen, lymph node, lung, and skin. Renal failure is another complication of MM due to myeloma kidney, uric acid nephropathy, hemoconcentration, or light chain disease. This study reported a case of MM with unusual presentation. She was a 61-year-old woman who was admitted to the internal ward due to severe renal failure, anemia, mild proteinuria, hypertension, thrombocytopenia, and soft tissue mass in both lungs in the spiral computed tomography (CT) scan. In the skull X-ray, there was not any lytic lesion. Further, plasma cells greater than 30% were observed in serum protein electrophoresis pick of gamma region and in the bone marrow aspiration, so the final diagnosis of the patients was MM with extramedullary plasmacytoma.
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表现不寻常的多发性骨髓瘤1例
髓外浆细胞瘤是多发性骨髓瘤(MM)的罕见并发症。MM的髓外受累部位包括肝脏、脾脏、淋巴结、肺和皮肤。肾衰竭是MM的另一个并发症,由骨髓瘤肾病、尿酸肾病、血液浓缩或轻链疾病引起。本研究报告一例异常表现的MM。患者是一名61岁的女性,因严重肾功能衰竭、贫血、轻度蛋白尿、高血压、血小板减少症和双肺软组织肿块在螺旋计算机断层扫描(CT)中被送入内科病房。颅骨x线片未见任何溶解性病变。血清蛋白电泳γ区和骨髓穿刺浆细胞均大于30%,故最终诊断为MM合并髓外浆细胞瘤。
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