Algorithm for History Reconstruction of Viral Recombination Events: Preliminary Results

Carlos Gomez, G. González, Esteban Meneses
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Abstract

An accurate understanding of the evolutionary history of virus species could help in the development of prevention measures or new treatments. Most current tools offer phylogenetic analysis focused on mutations as the main evolutionary mechanism and ignore inconsistencies caused by recombination events. This work intends to describe an algorithm for history reconstruction of recombination events detected from a set of viral genomic sequences. Preliminary results are provided from the analysis of some sequences of Human Adenovirus D with the proposed algorithm.
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病毒重组事件历史重建算法:初步结果
准确了解病毒物种的进化史有助于制定预防措施或新的治疗方法。目前大多数工具提供的系统发育分析侧重于突变作为主要的进化机制,而忽略了重组事件引起的不一致性。本工作旨在描述一种从一组病毒基因组序列中检测到的重组事件的历史重建算法。用该算法对部分人腺病毒D序列进行了分析,得到了初步结果。
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