FORMULASI DAN UJI STABILITAS FISIK TABLET KEMPA EKSTRAK DAUN PEPAYA ( Carica Papaya. L)

Beta Herilla Sekti, Agung Permata, Neysa Oktadiva S. P
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Abstract

Papaya leaf (Carica Papaya L.) is a plant that contains alkaloids, flavonoids, tripertinoids, saponins and tannins that are useful for treating diabetes. This study aims to obtain compressed tablets of papaya leaf extract and determine the effect of the concentration of PVP K30 as a binder on the physical properties of compressed tablets. The study used an experimental method, with a comparison of formula 1 = 1%, formula 2 = 3% and formula 3 = 5% and tested the physical properties of tablets. The results showed that the tablets met the requirements and only one formula did not meet the tablet friability test. The conclusion of the research on compressed tablets of papaya leaf extract with different concentrations of PVP K30 as a binder met the requirements for the physical test of tablets
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木瓜提取物(Carica Papaya)的配方和物理稳定性测试片。L)
番木瓜叶(Carica Papaya L.)是一种含有生物碱、类黄酮、三羧酸、皂苷和单宁的植物,对治疗糖尿病有用。本研究旨在获得番木瓜叶提取物的压缩片,并确定PVP K30作为粘结剂的浓度对压缩片物理性能的影响。本研究采用实验方法,将配方1 = 1%、配方2 = 3%、配方3 = 5%进行对比,测试片剂的物理性能。结果表明,所制片剂均符合要求,仅有1个配方不符合片剂脆碎试验要求。实验结果表明,以不同浓度的PVP K30为黏合剂制备的木瓜叶提取物压缩片剂符合片剂物理检测的要求
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