GET pathway mediates transfer of mislocalized tail-anchored proteins from mitochondria to the ER

S. Matsumoto, S. Ono, Saori Shinoda, Chika Kakuta, S. Okada, Takashi Ito, T. Numata, T. Endo
{"title":"GET pathway mediates transfer of mislocalized tail-anchored proteins from mitochondria to the ER","authors":"S. Matsumoto, S. Ono, Saori Shinoda, Chika Kakuta, S. Okada, Takashi Ito, T. Numata, T. Endo","doi":"10.1083/jcb.202104076","DOIUrl":null,"url":null,"abstract":"Tail-anchored (TA) membrane proteins mistargeted to mitochondria are extracted by Msp1 and then transferred to the ER for further quality control. Matsumoto, Ono, et al. show that this retransfer of mistargeted TA proteins requires the operation of the GET system.","PeriodicalId":343306,"journal":{"name":"The Journal of Cell Biology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Cell Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1083/jcb.202104076","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6

Abstract

Tail-anchored (TA) membrane proteins mistargeted to mitochondria are extracted by Msp1 and then transferred to the ER for further quality control. Matsumoto, Ono, et al. show that this retransfer of mistargeted TA proteins requires the operation of the GET system.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
GET途径介导错误定位的尾锚蛋白从线粒体转移到内质网
错误定位于线粒体的尾部锚定(TA)膜蛋白由Msp1提取,然后转移到内质网进行进一步的质量控制。Matsumoto、Ono等人表明,错靶TA蛋白的这种再转移需要GET系统的操作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
UBAP2L ensures homeostasis of nuclear pore complexes at the intact nuclear envelope BRG1 programs PRC2-complex repression and controls oligodendrocyte differentiation and remyelination. Unveiling the TRAPP: The role of plant TRAPPII in adaptive growth decisions. Calcium ions promote migrasome formation via Synaptotagmin-1. Determinants of minor satellite RNA function in chromosome segregation in mouse embryonic stem cells.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1