Orbitofrontal cortex damage effects in humans and other primates

E. Rolls
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Abstract

Impairments in the rapid reversal learning of stimulus-reward associations, when expected rewards are not obtained or punishers are obtained, are produced by damage to the orbitofrontal cortex; and contribute to the major changes in emotion, personality, and impulsiveness that can be produced by damage to the orbitofrontal cortex. Impairments in the processing of rewards are found, with alterations in food choice and eating, and in the identification of face and voice expressions, which are important for social behavior.
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眶额皮质损伤对人类和其他灵长类动物的影响
当没有获得预期的奖励或获得惩罚时,刺激-奖励关联的快速反向学习的损伤是由眶额皮质损伤引起的;并导致情绪、个性和冲动的重大变化,这些变化可能是由眶额叶皮层受损造成的。研究发现,在处理奖励过程中出现了缺陷,在食物选择和进食方面发生了变化,在识别对社会行为很重要的面部和声音表情方面也发生了变化。
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