Determination of efficacy of different Newcastle disease vaccine used in broiler chickens

J. Khanam, Md Mostafizer Rahman, M. Fakhruzzaman, N. Rumi
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Abstract

The present study was designed to determine the protection afforded by different vaccination programs against the Newcastle disease virus. A serological survey on the prevalence of antibodies to Newcastle disease virus (NDV) was carried out in broilers chicken in Dinajpur districts. For this reason, a total of 75 serum samples were collected form broiler chickens and samples were divided into five groups, each group contain 15 chickens. Group E did not receive any vaccine and served as a negative control group. Groups A-D were vaccinated with different vaccination programs against NDV. From this experimental work the principal objectives of the present investigation it may be stated that production of Hl-antibody was higher in birds of group D vaccinated with CevacVitapest-LR compared to those of group A vaccinated with Medivac NDLaSotaR, group B vaccinated with BCRDV(R) and group C vaccinated with Izovac. B, HitchnerR. Thus, the CevacVitapest-LR was found to be superior to some extent than Medivac ND-LaSota, BCRDVR, Izovac B, Hitchnert. However, as regards vaccination of chicks against NDV in earlier days the use of lentogenic strains are recommended although it should be kept in mind that vaccination with LaSota strains would cause considerately greater problems in young susceptable birds than Hitchner B1 strain and even through LaSota induces a stronger immune response. Asian Australas. J. Biosci. Biotechnol. 2018, 3 (1), 52-58
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不同新城疫疫苗对肉鸡的效力测定
本研究旨在确定不同疫苗接种方案对新城疫病毒的保护作用。对Dinajpur地区肉鸡进行了新城疫病毒(NDV)抗体的血清学调查。为此,共采集肉鸡血清标本75份,分为5组,每组15只鸡。E组不接种任何疫苗,作为阴性对照组。A-D组接种不同的NDV疫苗接种方案。从这项实验工作(本研究的主要目标)可以看出,与接种Medivac NDLaSotaR的A组、接种BCRDV(R)的B组和接种Izovac的C组相比,接种CevacVitapest-LR的D组的鸟类产生的hl抗体更高。B, HitchnerR。因此,我们发现CevacVitapest-LR在一定程度上优于Medivac ND-LaSota、BCRDVR、Izovac B、Hitchnert。然而,在雏鸡早期接种NDV疫苗时,建议使用lentogenic菌株,尽管应该记住,与Hitchner B1菌株相比,使用LaSota菌株接种疫苗会对易感雏鸟造成更大的问题,甚至通过LaSota诱导更强的免疫反应。亚洲Australas。j . Biosci。生物技术,2018,3 (1),52-58
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