術後, 肝転移に対する全身化学療法, ラジオ波焼灼療法による治療が奏効した胃腺扁平上皮癌の1例

The Japanese journal of gastro-enterology Pub Date : 2012-04-05 DOI:10.11405/NISSHOSHI.109.606

康弘福田, 史直竹島, 久美荻原, 寛之庄司, 祐子赤澤, 卓也堤, 邦子安倍, 陽平水田, 一磯本, 一彦中尾

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引用次数: 1

Abstract

: A 70-year-old man was given a diagnosis of advanced type 3 gastric cancer and underwent surgery. In addition to total gastrectomy and D2 lymph node resection, partial liver resection was performed due to detection of a solitary liver metastasis which was initially overlooked on preoperative CT. Histopathologically, the tumor was diagnosed as gastric adenosquamous carcinoma (Int, INFβ, pT2 (ss), H1, ly1, v2 (mp), EVG, n (-), pPM (-), pDM (-)). Three metastasic lesions appeared in the liver on abdominal CT scan performed 3 months after the operation. The patient underwent adjuvant chemotherapy with S-1. Since enlargement of the liver metastases was observed following 2 courses of treatment, the patient received combination chemotherapy of irinotecan and cisplatin. Of 3 metastatic lesions, 1 disappeared and 2 decreased to less than 2 cm in diameter after 8 courses of 2nd line treatment. Radiofrequency ablation (RFA) was successfully performed to treat the remaining liver metastases. The patient has been free of recurrence for 41 months.

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术后，针对肝转移的全身化疗和射频烧灼疗法的治疗奏效的胃腺鳞状细胞癌1例

一名70岁的男性被诊断为晚期3型胃癌并接受了手术。除全胃切除和D2淋巴结切除外，由于术前CT未发现单发肝转移，行部分肝切除。组织病理学诊断为胃腺鳞癌(Int、INFβ、pT2 (ss)、H1、ly1、v2 (mp)、EVG、n(-)、pPM(-)、pDM(-))。术后3个月腹部CT扫描显示肝脏3个转移灶。患者行S-1辅助化疗。治疗2个疗程后发现肝转移灶扩大，患者接受伊立替康联合顺铂化疗。3例转移灶中，经8个疗程的二线治疗后，1例转移灶消失，2例转移灶直径减小至小于2cm。射频消融(RFA)成功地治疗了剩余的肝转移灶。患者已41个月无复发。

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The Japanese journal of gastro-enterology

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