PRIMARY PERCUTANEOUS CORONARY INTERVENTION IN COVID-19 PATEINTS

B. Dhital, S. Regmi, B. Shrestha, Sovit Thapa, Shahid Murtaza
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Abstract

Background: Coronavirus Disease 2019 is global pandemic having high morbidity and mortality. It is thought that COVID-19 can predispose high thrombus burden and lead to Acute Coronary Syndrome. The aim of this study was to compare the symptoms, angiographic characteristics and procedural outcome in COVID-19 positive and COVID-19 negative patient undergoing percutaneous coronary intervention for acute coronary syndrome. Methods: All the data of 121 patients who were admitted at Chitwan Medical College on April 2020 to September 2020, suffering from acute coronary syndrome who underwent PCI were collected and compared with COVID-19 positive and negative patients using SPSS version 22. The categorical variables were presented as numbers or percentages (%) and continuous variables were presented as mean ± standard deviation. Results: Patient suffering with acute coronary syndrome with concurrent COVID-19 infections have more symptoms of fever (27.3% Vs 0.9%) and cough (27.3% Vs 2.8%, complications (45.5% Vs 7.3%), Mortality (36.4% Vs 0.9%), multi vessels thrombosis (27.3% Vs 2.8%) glycoprotein IIb/IIIa inhibitors use (27.3% Vs 0.14%) than non-COVID infection. Conclusions: Patient with acute coronary syndrome with concurrent COVID-19 infections have high complication rate, multivessel thrombosis and death.
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COVID-19患者的经皮冠状动脉介入治疗
背景:2019冠状病毒病是一种高发病率和高死亡率的全球性大流行疾病。人们认为COVID-19可导致血栓高负荷并导致急性冠状动脉综合征。本研究的目的是比较经皮冠状动脉介入治疗急性冠脉综合征的COVID-19阳性和COVID-19阴性患者的症状、血管造影特征和手术结果。方法:收集Chitwan医学院2020年4月至2020年9月收治的121例急性冠状动脉综合征行PCI的患者资料,并使用SPSS 22版软件与COVID-19阳性和阴性患者进行比较。分类变量以数字或百分比(%)表示,连续变量以均数±标准差表示。结果:急性冠状动脉综合征合并COVID-19感染患者的发热(27.3% Vs 0.9%)、咳嗽(27.3% Vs 2.8%)、并发症(45.5% Vs 7.3%)、死亡率(36.4% Vs 0.9%)、多血管血栓形成(27.3% Vs 2.8%)、糖蛋白IIb/IIIa抑制剂使用(27.3% Vs 0.14%)等症状均高于非COVID-19感染患者。结论:急性冠状动脉综合征并发COVID-19感染患者并发症发生率高、多支血管血栓形成及死亡。
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