[Comparative experimental animal studies for testing the usefulness of formalin- and glutaraldehyde-pretreated umbilical cord veins as artery replacements].

Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR Pub Date : 1990-01-01

W Wagner, M Zieger, M Bartel, G Raabe, H Rimpler, T Aramayo

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Abstract

Formalin-fixed (F) and glutaraldehyde-pretreated (G) umbilical veins (n = 24) were interposed in the infra-renal aorta of dogs. The follow-up period was 1 year. Early complications with significant differences included 2 occlusions and 3 deaths (41.6%) in group F, 1 occlusion and 1 death (16.6%) in group G. Ten animals of group G and 7 of group F were alive at 1 year, 7 transplants of each of both groups were angiographically and macroscopically patent (25%). Four aneurysms (33.3%) existed angiographically and showed good collateral circulation angiographically (25%). Four aneurysms (33.3%) existed angiographically and macroscopically in group F (statistically significant). Histologically, group G was found to have a delayed resorption and an earlier beginning of connective-tissue proliferation as compared to group F. Considering early and late findings, G-pretreatment is preferable to F-treatment of umbilical veins.

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[测试福尔马林和戊二醛预处理脐带静脉作为动脉替代物的有效性的比较实验动物研究]。

将福尔马林固定(F)和戊二醛预处理(G)的脐静脉(n = 24)置入肾下主动脉。随访1年。早期并发症F组有2例闭塞3例死亡(41.6%)，G组有1例闭塞1例死亡(16.6%)，G组1年存活10例，F组7例，两组各7例移植血管造影和宏观通畅(25%)。血管造影显示4个动脉瘤(33.3%)存在，血管造影显示侧枝循环良好(25%)。F组经血管造影及宏观检查发现动脉瘤4个(33.3%)，差异有统计学意义。组织学上，与f组相比，G组吸收延迟，结缔组织增殖开始较早。考虑到早期和晚期的发现，G预处理优于f治疗脐静脉。

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Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR

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