The Gastrointestinal Barrier

R. Bowen
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Abstract

The gastrointestinal mucosa forms a barrier between the body and a lumenal environment which not only contains nutrients, but is laden with potentially hostile microorganisms and toxins. The challenge is to allow efficient transport of nutrients across the epithelium while rigorously excluding passage of harmful molecules and organisms into the animal. The exclusionary properties of the gastric and intestinal mucosa are referred to as the "gastrointestinal barrier".
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胃肠道屏障
胃肠道粘膜在身体和肠道环境之间形成屏障,肠道环境不仅含有营养物质,而且充满了潜在的有害微生物和毒素。挑战在于允许营养物质有效地通过上皮运输,同时严格排除有害分子和生物体进入动物体内。胃和肠粘膜的排斥性被称为“胃肠道屏障”。
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