Effect of Carboprost Tromethamine Combined with Uterine Strap Suture in the Treatment of Patients with Postpartum Hemorrhage Caused by Uterine Atony

Abstract

Objective: To explore and analyze the effect of carboprost tromethamine combined with uterine strap suturein the treatment of postpartum hemorrhage caused by uterine atony. Methods: A total of 90 patients with postpartum hemorrhage due to uterine atony who were admitted to the Obstetrics Department of Dazhou Women and Children’s Hospital from July 2020 to July 2023 were included in the study. They were grouped by odd and even numbers, and divided into the surgery group (n = 45) and the drug group (n = 45). The surgery group was treated with carboprost tromethamine and uterine strap suture, and the drug group was treated with carboprost tromethamine. The total effective rate, blood coagulation index, fibrinolytic function level, bleeding, and hemoglobin changes were compared between the two groups. Results: The total effective rate of the surgery group was significantly higher than that of the medication group (P < 0.05). Before treatment, the blood coagulation indicators were insignificant between the groups (P > 0.05); after treatment, the blood coagulation indicators in the surgery group were significantly better than those in the drug group (P < 0.05). Before treatment, the levels of fibrinolytic functions were insignificant between the groups (P > 0.05); aftertreatment, the levels of fibrinolytic functions in the surgery group were significantly better than those in the drug group (P < 0.05). The 2 h and 24 h blood loss and hemoglobin changes in the surgery group were significantly lower than those in the drug group (P < 0.05). Conclusion: Carboprost tromethamine combined with strap sutures can effectively control postpartum hemorrhage caused by uterine atony.