Obstructive Sleep Apnoea as an Exacerbator of Vasospastic Angina

Faith Michael, Anthony Main, Andreas Kumar
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Abstract

Little is known about the association between obstructive sleep apnoea (OSA) and vasospastic angina. The authors report the case of a 47-year-old female with vasospastic angina who had a high symptom burden despite nitroglycerine and a calcium channel blocker. After a sleep study revealed severe OSA, the patient was started on continuous positive airway pressure. Following 8 weeks of continuous positive airway pressure, the patient reported remarkable improvement in their symptoms. This case suggests an under-recognised link between OSA and vasospastic angina. While further clinical research is required, screening and treatment of OSA may be beneficial for patients with treatment refractory vasospastic angina.
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阻塞性睡眠呼吸暂停是血管痉挛性心绞痛的加重因素
阻塞性睡眠呼吸暂停(OSA)与血管痉挛性心绞痛之间的关系知之甚少。作者报告了一例47岁女性血管痉挛性心绞痛患者,尽管服用了硝酸甘油和钙通道阻滞剂,但症状负担仍然很高。在睡眠研究发现严重的阻塞性睡眠呼吸暂停后,患者开始持续气道正压通气。持续气道正压治疗8周后,患者报告症状明显改善。本病例提示阻塞性睡眠呼吸暂停与血管痉挛性心绞痛之间的联系尚未得到充分认识。虽然需要进一步的临床研究,但OSA的筛查和治疗可能对治疗难治性血管痉挛性心绞痛的患者有益。
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