Case Report: Diagnosis and Therapy Technique for Dirofilariasis – Ehrlichiosis Coinfection in a Domestic Dog

Joan Elviyanti, Arief Purwo Mihardi, Anita Esfandiari, Rizal Arifin Akbari
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Abstract

Multiple pathogenic agents, such as dirofilariasis and ehrlichiosis coinfection in the dog, cause coinfection disease. This paper aims to elucidate the diagnosis and therapy technique of dirofilariasis and ehrlichiosis coinfection disease in a dog. The owner brought a 4-year-old female dog named Lua to Rvet Clinic Tajur Halang Bogor with complaints of always painting when doing activities and lying down. The dog was just adopted one month from the shelter with many ticks and mosquitoes in the cage. The dog was diagnosed with dirofilariasis and ehrlichiosis by physical examination and laboratory tests. The laboratory tests included radiography, haematology, blood smear, and antigen test by SNAP® 4Dx® Plus Test (IDEXX, US). The dog was given doxycycline 10 mg/kg BW BID orally for three weeks, vitamin B12 0.025mg/kg BW BID orally for three weeks, furosemide 2 mg/kg BW SID orally for one week, Coenzyme-Q10 SID orally for three weeks, and selamectin topical drop every month for three months. A blood smear on the 21st day after therapy did not show microfilariae in 20 hpf with three repetitions. It means the therapy combinations are used effectively to reduce microfilariae and maintain the clinical sign of a dog due to dirofilariasis accompanied by ehrlichiosis.
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家犬双丝虫病-埃利希体病合并感染的诊治技术报告
犬双丝虫病和埃利希体病合并感染等多种病原可引起合并感染。本文旨在阐述犬双丝虫病和埃利希体病合并感染的诊断和治疗方法。主人带着一只名叫Lua的4岁母狗来到Tajur Halang Bogor的Rvet诊所,抱怨它在活动和躺下时总是画画。这只狗刚被收养一个月,笼子里有很多虱子和蚊子。经体格检查和实验室检查,该犬被诊断为双丝虫病和埃利希体病。实验室检查包括x线摄影、血液学、血液涂片和SNAP®4Dx®Plus test (IDEXX,美国)抗原检测。给予强力霉素10 mg/kg BW BID口服3周,维生素B12 0.025mg/kg BW BID口服3周,呋塞米2 mg/kg BW SID口服1周,辅酶q10 SID口服3周,selamectin每月外用滴剂,连续3个月。治疗后第21天的血液涂片在20 hpf中未显示微丝蚴,重复3次。这意味着治疗组合有效地减少了微丝虫病,并维持了狗因双丝虫病伴埃利希体病而出现的临床症状。
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