Polymeric Chitosan/Poly (Vinyl Alcohol) Hybrid Doped with Zinc Oxide Nanoparticles Synthesized and Characterized Using the Electrospun Method

Journal of University of Babylon Pub Date : 2023-09-30 DOI:10.29196/jubpas.v31i3.4850

Ali L. Alfalluji, Qasim Shakir Kadhim, Jehan Hamzah Hussein

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Abstract

Background:Because of their portability and flexibility in altering surface properties, nanofibers have attracted more attention in recent years, particularly in biological applications. The development of affordable antibacterial base agents for wound healing capabilities and other medical technologies is still in high demand. Porosity, ease of forming into different sizes, and high surface area are just a few of the benefits of nanofibers.Materials and Methods:A 90% deacetylated (average 200,000 MW) poly(vinyl alcohol) chitosan with a life of 72000 MW was bought.Results:Through the samples of the electronic scanner, electrospinning rates, flow of 0.6 ml / sec, voltage of 10 kV, distance between the collector and the needle of 8 cm, and the ratio of PVA / CS / ZnO to the polymer with the addition of nanoparticles ratio 0.4% 65 / 35.Conclusion:In this study, the nanofiber compound PVA / CS / ZnO proved to have medical and biological compatibility. There is no toxicity in this compound. It has therapeutic properties against microbes and is good in healing wounds, as in previous studies

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用静电纺丝法合成了掺杂氧化锌纳米粒子的聚合壳聚糖/聚乙烯醇杂化物并进行了表征

背景:纳米纤维由于其可移植性和改变表面特性的灵活性，近年来受到越来越多的关注，特别是在生物领域的应用。开发负担得起的抗菌基础剂用于伤口愈合能力和其他医疗技术仍然有很高的需求。多孔性、易于形成不同尺寸、高表面积只是纳米纤维的几个优点。材料与方法:购买了90%脱乙酰化(平均20000mw)聚乙烯醇壳聚糖，其寿命为72000mw。结果:通过电子扫描，样品的静电纺丝速率，流速为0.6 ml / sec，电压为10 kV，收集器与针头之间的距离为8 cm, PVA / CS / ZnO与聚合物的比例为添加纳米颗粒的比例为0.4% 65 / 35。结论:PVA / CS / ZnO纳米纤维复合材料具有良好的医用和生物相容性。这种化合物没有毒性。正如之前的研究，它具有抗微生物的治疗特性，对伤口愈合有好处

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Journal of University of Babylon

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