Celine Ng, Mohd Syahir Anwar Hamzah, Nadirul Hasraf Mat Nayan
{"title":"Potential Role of Bromelain in Wound Healing Application: A Review","authors":"Celine Ng, Mohd Syahir Anwar Hamzah, Nadirul Hasraf Mat Nayan","doi":"10.30880/ijie.2023.15.04.001","DOIUrl":null,"url":null,"abstract":"Bromelain is a proteolytic enzyme derived from the pineapple plant (Ananas comosus). Bromelain can be extracted from pineapple stems and fruits. Additionally, it can be derived from pineapple wastes such as the core, crown, and peel. Various extraction and purification methods such as reverse micellar system, aqueous two-phase system, chromatographic techniques, and membrane filtration have been used in order to produce high-qualitybromelain. Bromelain has been used clinically since 1876 and was first introduced as a therapeutic agent in 1957. Bromelain has gained increasing acceptance and compliance among patients as a phytotherapeutic drug due to its safety and lack of undesirable side effects. Bromelain is regarded as a nutrient that promotes wound healing due to the presence of several closely related proteinases that exhibit anti-inflammatory, fibrinolytic, and debridement properties.","PeriodicalId":14189,"journal":{"name":"International Journal of Integrated Engineering","volume":"71 1","pages":"0"},"PeriodicalIF":0.4000,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Integrated Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30880/ijie.2023.15.04.001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Bromelain is a proteolytic enzyme derived from the pineapple plant (Ananas comosus). Bromelain can be extracted from pineapple stems and fruits. Additionally, it can be derived from pineapple wastes such as the core, crown, and peel. Various extraction and purification methods such as reverse micellar system, aqueous two-phase system, chromatographic techniques, and membrane filtration have been used in order to produce high-qualitybromelain. Bromelain has been used clinically since 1876 and was first introduced as a therapeutic agent in 1957. Bromelain has gained increasing acceptance and compliance among patients as a phytotherapeutic drug due to its safety and lack of undesirable side effects. Bromelain is regarded as a nutrient that promotes wound healing due to the presence of several closely related proteinases that exhibit anti-inflammatory, fibrinolytic, and debridement properties.
期刊介绍:
The International Journal of Integrated Engineering (IJIE) is a single blind peer reviewed journal which publishes 3 times a year since 2009. The journal is dedicated to various issues focusing on 3 different fields which are:- Civil and Environmental Engineering. Original contributions for civil and environmental engineering related practices will be publishing under this category and as the nucleus of the journal contents. The journal publishes a wide range of research and application papers which describe laboratory and numerical investigations or report on full scale projects. Electrical and Electronic Engineering. It stands as a international medium for the publication of original papers concerned with the electrical and electronic engineering. The journal aims to present to the international community important results of work in this field, whether in the form of research, development, application or design. Mechanical, Materials and Manufacturing Engineering. It is a platform for the publication and dissemination of original work which contributes to the understanding of the main disciplines underpinning the mechanical, materials and manufacturing engineering. Original contributions giving insight into engineering practices related to mechanical, materials and manufacturing engineering form the core of the journal contents.