Rate of Conversion of Conservative Breast Surgery to Mastectomy in Patients with Early Breast Cancer Versus Late Breast Cancer after Down Staging

Abstract

Background: After lung cancer, breast cancer is the most frequent cancer among women and the second greatest cause of cancer death. Aim of Study: The rate and causes of breast conservative surgery conversion to mastectomy in early breast cancer versus down staging after neoadjuvant treatment are identified. Patients and Methods: During this study, 40 females with breast cancer were enrolled and divided into two groups. All patients were subjected to conservative breast surgery and intraoperative frozen section; 20 patients with early breast cancer andanother 20 patients who received neoadjuvant therapy. All patients were subjected to history taking, clinical examination, radiologic investigations, core biopsy, preoperative laboratory investigations and histopathological examination of excised mass. Results: There were no statistically significant differences between study groups as regard rate of conversion to mastectomy, frozen results, post-operative compilations and response and Clipping distribution. Conclusion: The rate of conversion to mastectomy, frozen results, post-operative compilations and response, and clipping distribution were similar in cases of early breast cancer and late stages subjected to neoadjuvant down staging treatment. As a result, all cases of late breast cancer were down staged using neoadjuvant therapy rather than undergoing mastectomy.