The application advances of dendrimers in biomedical field

IF 9.7 4区 医学 Q1 MATERIALS SCIENCE, BIOMATERIALS VIEW Pub Date : 2023-09-18 DOI:10.1002/viw.20230023
Longjie Li, Yukai Deng, Yonghui Zeng, Bei Yan, Yulian Deng, Ziyang Zheng, Siqi Li, Yuhang Yang, Jinwei Hao, Xianjin Xiao, Xinyu Wang
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Abstract

Abstract Dendrimers are a family of nano‐sized three‐dimensional polymers with unique dendritic branching structures and compact spherical geometries. In recent years, dendrimers have made a series of breakthroughs in the biomedical field. In this review, we introduce the synthesis principles, modification methods, and new materials designed based on dendrimers; discuss the importance of cytotoxicity of dendrimers for applications; and elaborate on their applications in the field of molecular assembly and cancer diagnosis and treatment. We speculate that in the near future, more new materials based on dendrimers will be applied in the biomedical field.

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树状大分子在生物医学领域的应用进展
树状大分子是一类具有独特枝状分支结构和紧凑的球形几何形状的纳米级三维聚合物。近年来,树突状分子在生物医学领域取得了一系列突破。本文主要介绍了树状大分子的合成原理、改性方法以及基于树状大分子设计的新材料;讨论了树状大分子细胞毒性在应用中的重要性;并详细阐述了它们在分子组装和癌症诊断与治疗领域的应用。我们推测,在不久的将来,更多基于树状大分子的新材料将应用于生物医学领域。
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来源期刊
VIEW
VIEW Multiple-
CiteScore
12.60
自引率
2.30%
发文量
0
审稿时长
10 weeks
期刊介绍: View publishes scientific articles studying novel crucial contributions in the areas of Biomaterials and General Chemistry. View features original academic papers which go through peer review by experts in the given subject area.View encourages submissions from the research community where the priority will be on the originality and the practical impact of the reported research.
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