Improved Antiproliferative Activity of Doxorubicin-Loaded Calcium Phosphate Nanoparticles Against Melanoma Cells

IF 1 4区 生物学 Q3 BIOLOGY Brazilian Archives of Biology and Technology Pub Date : 2023-01-01 DOI:10.1590/1678-4324-2023220572
Igor Barbosa Lima, Betania Mara Alvarenga, Priscila Izabel Santos de Tótaro, Fernanda Boratto, Elaine Amaral Leite, Pedro Pires Goulart Guimaraes
{"title":"Improved Antiproliferative Activity of Doxorubicin-Loaded Calcium Phosphate Nanoparticles Against Melanoma Cells","authors":"Igor Barbosa Lima, Betania Mara Alvarenga, Priscila Izabel Santos de Tótaro, Fernanda Boratto, Elaine Amaral Leite, Pedro Pires Goulart Guimaraes","doi":"10.1590/1678-4324-2023220572","DOIUrl":null,"url":null,"abstract":"HIGHLIGHTS N-Dox has higher activity against A-375 cells than free doxorubicin. The formulation has higher selectivity indices than free doxorubicin. Treatment induced senescence and no colonies recovered after short-term exposure.","PeriodicalId":9169,"journal":{"name":"Brazilian Archives of Biology and Technology","volume":"158 1","pages":"0"},"PeriodicalIF":1.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Archives of Biology and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/1678-4324-2023220572","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 1

Abstract

HIGHLIGHTS N-Dox has higher activity against A-375 cells than free doxorubicin. The formulation has higher selectivity indices than free doxorubicin. Treatment induced senescence and no colonies recovered after short-term exposure.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
负载阿霉素的磷酸钙纳米颗粒对黑色素瘤细胞的抗增殖活性提高
N-Dox对A-375细胞的活性高于游离阿霉素。该制剂具有比游离阿霉素更高的选择性指标。处理引起衰老,短期暴露后没有菌落恢复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
1.80
自引率
0.00%
发文量
116
审稿时长
3 months
期刊介绍: Information not localized
期刊最新文献
Societal Factors and Teen Dating Violence: a Scoping Review. Multi-objective Sand Piper Optimization Based Clustering with Multihop Routing Technique for IoT Assisted WSN Estimation of Genetic Variance Components for Corn Ear Rot in RIL Populations Derived from Three Biparental Crosses Oral Yeast Load and Species of Young Individuals Aged 18-25 Diallel Analysis of Dry Bean Varieties for Seed Yield and Important Traits for Calcareous Soils
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1