Evaluation of Newly Formulated Chlorhexidine Mouthwash

IF 0.5 Q4 ENGINEERING, BIOMEDICAL Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-10-24 DOI:10.4028/p-dppua9
Peerapong Tua-Ngam, Ratchaporn Srichan, Arthit Klaophimai, Pachara Rudrakanjana, Thanattha Wuttihasa, Rattiporn Kaypetch
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引用次数: 0

Abstract

Chlorhexidine gluconate mouthwash has a poor taste during and after rinsing which makes its users dissatisfied. Therefore, the product must be improved to have a better taste and still retain its effectiveness against oral pathogens. To evaluate in vitro antimicrobial activity and toxicity effects of Newly formulated chlorhexidine mouthwash. The antimicrobial activity of the mouthwash was evaluated by Agar well diffusion method against the tested microorganisms. The toxicity test was performed by using the MTT assay. The new formula has the potential to treat and prevent oral and throat infections. The newly developed Chlorhexidine mouthwash can be considered safe for oral usage.
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新配方洗必泰漱口水的评价
葡萄糖酸氯己定漱口水在冲洗时和冲洗后的味道都很差,使使用者不满意。因此,必须对产品进行改进,使其口感更好,同时保持其对口腔病原体的有效性。评价新配制的氯己定漱口水的体外抗菌活性和毒性作用。采用琼脂孔扩散法评价漱口水对被试微生物的抑菌活性。采用MTT法进行毒性试验。这种新配方具有治疗和预防口腔和咽喉感染的潜力。新研制的氯己定漱口水可安全口服。
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来源期刊
CiteScore
1.40
自引率
14.30%
发文量
73
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