THE ROLE OF THE GUT MICROBIOME IN THE DEVELOPMENT OF COLORECTAL CANCER AND THE OCCURENCE OF THE ANASTOMOTIC LEAK IN THE POSTOPERATIVE PERIOD

Abstract

Colorectal cancer (CRC) is a common disease with a high mortality rate. CRC is the third most common disease in the world in men and the second most common disease in women, according to the World Health Organization. There is currently an increased interest in studying the relationship between the gut microbiome and the development of CRC. Changes in the gut microbiome in patients with CRC suggest a possible role of host-microbe interactions in the onset and development of this malignancy and, at the same time, open possibilities for new ways of preventing, diagnosing and treating this disease. This review aims to consider certain aspects of the influence of the gut microbiome on the development of CRC and some related diseases.