The Effect of Treatment on Weight Gain in Iron Deficiency Anemia and Its Association with Ghrelin and Hepcidin Levels

Q4 Medicine Duzce Medical Journal Pub Date : 2023-10-04 DOI:10.18678/dtfd.1323406
Halil Cansun KILINÇ, Birgül ÖNEÇ, Kursad ONEC, Handan ANKARALI
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 Material and Methods: Eighty-seven adult patients with IDA and a control group of 50 healthy volunteers were included in the study. Anthropometric measurements and blood samples were obtained from the patient and control groups before treatment, and repeated after treatment in the IDA group.
 Results: No significant difference was found in terms of weight, body mass index (BMI), and waist-to-hip ratio between groups but there was a significant increase in weight and BMI, in the patient group after treatment (both p","PeriodicalId":53622,"journal":{"name":"Duzce Medical Journal","volume":"20 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Duzce Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18678/dtfd.1323406","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
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Abstract

Aim: Although loss of appetite in iron deficiency anemia (IDA) and weight gain during treatment are common complaints, there are very few studies in adults. This study aimed to determine the levels of ghrelin, one of the appetite-related hormones, and hepcidin, one of the main regulators of iron metabolism, in IDA, and to examine the effects of treatment on weight gain and the levels of these hormones. Material and Methods: Eighty-seven adult patients with IDA and a control group of 50 healthy volunteers were included in the study. Anthropometric measurements and blood samples were obtained from the patient and control groups before treatment, and repeated after treatment in the IDA group. Results: No significant difference was found in terms of weight, body mass index (BMI), and waist-to-hip ratio between groups but there was a significant increase in weight and BMI, in the patient group after treatment (both p
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治疗对缺铁性贫血体重增加的影响及其与Ghrelin和Hepcidin水平的关系
目的:尽管缺铁性贫血(IDA)患者食欲不振和治疗期间体重增加是常见的主症,但很少有针对成人的研究。本研究旨在确定IDA中胃饥饿素(一种与食欲相关的激素)和铁代谢的主要调节因子hepcidin的水平,并研究治疗对体重增加和这些激素水平的影响。 材料与方法:87例成年IDA患者和50名健康志愿者作为对照组。治疗前分别对患者和对照组进行人体测量和血液采样,治疗后对IDA组进行重复。 结果:两组患者的体重、体重指数(BMI)、腰臀比均无显著差异,但患者组治疗后体重、BMI均有显著升高(p
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来源期刊
Duzce Medical Journal
Duzce Medical Journal Medicine-Medicine (all)
CiteScore
0.60
自引率
0.00%
发文量
59
审稿时长
12 weeks
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