Efficacy of Platelet Rich Plasma in Erectile Dysfunction: A Clinical Trial

Asma Tasnim Khan, Md Abul Hashem, Muhammed Kamrul Hassan, Mahfuja Jakia, Nayanmani Sarkar, Mohammad Irfan Ullah Sakib, Sharmin Jahan
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Abstract

Background: Platelet-rich plasma (PRP) is a treatment that uses a patient's own blood, processed to concentrate platelets and growth factors, to treat erectile dysfunction (ED). Erectile dysfunction (ED) is a common condition that affects men of all ages and can have a significant impact on quality of life. Platelet rich plasma (PRP) is a newer treatment option that involves injecting a concentrated solution of platelets into the affected area to promote healing and tissue regeneration. Objective: The purpose of the present study was to evaluate the efficacy of platelet-rich plasma (PRP) in treating erectile dysfunction (ED). Methodology: A prospective study was conducted to evaluate the efficacy of platelet-rich plasma (PRP) in treating erectile dysfunction (ED) with a sample of 50 patients in Dhaka, Bangladesh during the period of January 2022 to June 2022. The patients received PRP treatment and the improvement in erectile function was measured through standardized questionnaires and scales. Data were collected predesigned data collection sheet. Results: The average age of the study subjects is 53.70 years. The mean scores of the IIEF-EF domain showed a statistically significant improvement from 18.50 ± 3.60 before the procedure to 20.71 ± 3.71 after 6th months (p = 0.002). Sexual satisfaction also showed a statistically significant improvement, with a mean score increasing from 6.00 ± 0.57 before the procedure to 8.00 ± 0.85 after 6th months (p = 0.016). However, there were no statistically significant changes in the mean scores for orgasmic function and sexual desire (p = 0.113 and p = 0.389, respectively). The mean score for general satisfaction showed a small but statistically significant increase from 5.00 ± 0.29 before the procedure to 5.38 ± 0.24 after the 1st month (p = 0.027). Conclusion: In conclusion platelet-rich plasma (PRP) application provides short-term improvement in erectile function. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):71-75
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富血小板血浆治疗勃起功能障碍的临床研究
背景:富血小板血浆(PRP)是一种利用患者自身血液,浓缩血小板和生长因子来治疗勃起功能障碍(ED)的治疗方法。勃起功能障碍(ED)是一种影响所有年龄段男性的常见疾病,并对生活质量产生重大影响。富血小板血浆(PRP)是一种较新的治疗选择,它涉及将浓缩的血小板溶液注射到患处,以促进愈合和组织再生。目的:评价富血小板血浆(PRP)治疗勃起功能障碍(ED)的疗效。方法:在2022年1月至2022年6月期间,对孟加拉国达卡的50名患者进行了一项前瞻性研究,以评估富血小板血浆(PRP)治疗勃起功能障碍(ED)的疗效。患者接受PRP治疗,并通过标准化问卷和量表测量勃起功能的改善情况。数据收集是预先设计好的数据收集表。结果:研究对象平均年龄53.70岁。IIEF-EF域平均评分由术前的18.50±3.60分提高至6个月后的20.71±3.71分,差异有统计学意义(p = 0.002)。性满意度也有统计学意义上的改善,平均评分从术前的6.00±0.57分提高到6个月后的8.00±0.85分(p = 0.016)。而性高潮功能和性欲的平均得分差异无统计学意义(p = 0.113和p = 0.389)。总体满意度平均评分由术前的5.00±0.29分上升至术后1个月的5.38±0.24分,差异有统计学意义(p = 0.027)。结论:应用富血小板血浆(PRP)可短期改善勃起功能。孟加拉国国家神经科学研究所杂志,2023年1月;9(1):71-75
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