Use of Tranexamic Acid in Trauma in a Prehospital Context

Robson Natario Silveira Filho, Thomaz de Carvalho Lima Paiva, Breno Vasconcelos Lima Tenório França, Pedro Henrique Lins de Almeida, Savyo Firmino de Oliveira Costa, Gabriel Oliveira Ferro, Pedro Cavalcante Rocha, Annie Lis de Lima Ferreira, Maria Luiza Lima Cordeiro de Castro, Isadora Oliveira Barbosa, Laura Beatriz Tenorio Vitorino, Alice Cardoso Braga, Nycolle Beatriz Lima de Siqueira, Izadora Magalhães Vasconcellos, Matheus Pedrosa Cavalcante
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Abstract

Introduction: Tranexamic acid (TXA) is indicated for the control and prevention of hyperfibrinolysis-induced hemorrhages because it promotes increased clot stability. 11 Since its pre-hospital use is not yet well-defined, the purpose of this article is to evaluate the scientific research on its mechanism of action, indications, and contraindications to supplement the risk-benefit discussion. Methodology: The current study is a literature review, the database of which was taken from the SciELO (Scientific Electronic Library Online) and Pub Medplatforms.
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院前外伤中氨甲环酸的应用
简介:氨甲环酸(TXA)是指控制和预防高纤溶引起的出血,因为它促进增加凝块稳定性。由于其院前使用尚未明确,本文的目的是评估其作用机制、适应症和禁忌症的科学研究,以补充风险-收益讨论。方法学:本研究为文献综述,数据库来自SciELO(科学电子图书馆在线)和Pub medplatform。
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