Symptomatic treatment of cough in children

Q4 Medicine Meditsinskiy Sovet Pub Date : 2023-10-31 DOI:10.21518/ms2023-325
N. A. Geppe, A. R. Denisova, V. D. Denisova, N. G. Kolosova, I. V. Grebeneva
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Abstract

Cough is one of the most common symptoms in paediatric practice. Cough nature, duration, intensity, frequency, time and cause of occurrence should be considered in the differential diagnosis of its causes. Sputum evacuation disorders and changes in its rheological properties are indications for the prescription of mucoactive drugs. Despite the fact that the drugs included in this group have different mechanisms of action, all of them restore mucociliary clearance and lead to effective evacuation of secretions from the respiratory tract. Herbal medicinal products can be used along with classic mucoactive drugs (mucolytics, mucopegulators and mucokinetics). Ivy leaves are an example of a well-known and meticulously researched source of phytopharmaceutical products, they are included in the ESCOP monograph and entered into the positive list of the German Commission E. The efficacy and safety of ivy leaf products have been demonstrated in various controlled clinical studies. The authors presented a review of published clinical studies and non-interventional studies involving a total of 65,383 patients suffering from both acute and chronic respiratory diseases. The studies demonstrated the efficacy of ivy leaf extract preparations as achievement of a higher level of bronchodilation and surfactant production, which led to bronchospasmolytic, secretolytic, expectorant and, in turn, antitussive action. Herbal medicinal products are now actively used in the treatment of new coronavirus infection. Hedelix is one of the ivy leaf extract pharmaceutical preparations approved for use in children over the age of two years.
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小儿咳嗽的对症治疗
咳嗽是儿科实践中最常见的症状之一。病因鉴别诊断应考虑咳嗽的性质、持续时间、强度、频率、时间和发生原因。痰液排出障碍及其流变学性质的改变是使用黏液活性药物的适应症。尽管该组药物的作用机制不同,但它们都能恢复粘膜纤毛的清除,并导致呼吸道分泌物的有效排出。草药产品可以与经典的黏液活性药物(黏液解药、黏液调节剂和黏液动力学)一起使用。常青藤叶是一种众所周知的、经过精心研究的植物药产品来源,它们被列入ESCOP专著,并进入德国委员会e的正面清单。常青藤叶产品的有效性和安全性已在各种对照临床研究中得到证明。作者对已发表的临床研究和非介入性研究进行了回顾,共涉及65,383名患有急性和慢性呼吸道疾病的患者。研究表明,常青藤叶提取物制剂的功效是实现更高水平的支气管扩张和表面活性剂的生产,从而导致支气管解痉,解分泌,祛痰,进而止咳作用。目前,草药产品正积极用于治疗新型冠状病毒感染。Hedelix是一种被批准用于两岁以上儿童的常青藤叶提取物药物制剂。
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来源期刊
Meditsinskiy Sovet
Meditsinskiy Sovet Medicine-Medicine (all)
CiteScore
0.70
自引率
0.00%
发文量
418
审稿时长
6 weeks
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