[Cytokines: present and future therapeutic applications].

Giornale italiano di chemioterapia Pub Date : 1989-01-01
F De Benedetti, G L Marseglia, A Martini, G R Burgio
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Abstract

Recent technological developments have led in the the last years to the isolation and characterization of a group of polypeptides, generally termed cytokines, which are produced by cells of the immune system, and by other cell types; these peptides regulate the immune response and the inflammatory reaction, and, in general, cellular growth and differentiation. Because of the availability of large quantities of these cytokines, produced with recombinant DNA techniques, their use in therapy is now possible; promising results have been obtained in some diseases.

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[细胞因子:现在和未来的治疗应用]。
最近几年的技术发展导致了一组多肽的分离和表征,通常被称为细胞因子,它是由免疫系统细胞和其他细胞类型产生的;这些肽调节免疫反应和炎症反应,一般来说,细胞生长和分化。由于这些细胞因子的大量可用性,通过重组DNA技术生产,它们在治疗中的应用现在是可能的;在一些疾病中已经取得了可喜的结果。
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