Alternaria fungal dacryocystitis with cutaneous fistula: a case report.

Leslie Huang, Katherine F Dalzotto, Mark T Duffy, Jaclyn Gurwin, Suzanne W van Landingham
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Abstract

Alternaria is a fungal genus that can cause opportunistic human infection in immunocompromised hosts. While the majority of clinical manifestations are cutaneous or subcutaneous infections, there are reports of oculomycosis, which is most commonly present as keratomycosis or endophthalmitis.Here, we present a rare case of Alternaria dacryocystitis with cutaneous fistula in a diabetic patient. The patient was referred with a non-healing medial canthal wound and an initial biopsy report showing "ruptured hair follicle;" re-examination of the biopsy specimen with fungal stains led to the diagnosis of alternariosis. The patient underwent surgical debridement and systemic antifungal treatment, with complete resolution of the infection. In order to initiate prompt treatment and prevent invasive disease, fungal infection should be considered in an immunocompromised patient with chronic dacryocystitis and cutaneous fistula or a nonhealing medial canthus wound.

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互生真菌性泪囊炎伴皮瘘1例。
Alternaria是一种真菌属,可在免疫功能低下的宿主中引起机会性人类感染。虽然大多数临床表现为皮肤或皮下感染,但也有眼菌病的报道,最常见的是角膜痂病或眼内炎。在此,我们报告一个罕见的糖尿病患者的泪囊炎并发皮瘘的病例。患者因内侧眦伤口未愈合而转诊,最初的活检报告显示“毛囊破裂”,对活检标本进行真菌染色的重新检查,诊断为异生菌病。患者接受手术清创和全身抗真菌治疗,感染完全消失。为了及时治疗和预防侵袭性疾病,对于患有慢性泪囊炎和皮瘘或内侧眼角伤口未愈合的免疫功能低下患者,应考虑真菌感染。
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来源期刊
CiteScore
2.40
自引率
9.10%
发文量
136
期刊介绍: Orbit is the international medium covering developments and results from the variety of medical disciplines that overlap and converge in the field of orbital disorders: ophthalmology, otolaryngology, reconstructive and maxillofacial surgery, medicine and endocrinology, radiology, radiotherapy and oncology, neurology, neuroophthalmology and neurosurgery, pathology and immunology, haematology.
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