Optimizing cardiac status in the preliver transplant candidate.

IF 1.8 4区 医学 Q3 TRANSPLANTATION Current Opinion in Organ Transplantation Pub Date : 2024-02-01 Epub Date: 2023-11-14 DOI:10.1097/MOT.0000000000001119
Maxine W Stachel, Eugene C DePasquale
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Abstract

Purpose of review: Liver transplant is a widely accepted therapy for end-stage liver disease. With advances in our understanding of transplant, candidates are increasingly older with more cardiac comorbidities. Cardiovascular disease also represents a leading cause of morbidity and mortality posttransplant.

Recent findings: Preoperative cardiac risk stratification and treatment may improve short-term and long-term outcomes after liver transplant. Importantly, the appropriate frequency of surveillance has not been defined. Optimal timing of cardiac intervention in end-stage liver disease is likewise uncertain.

Summary: The approach to risk stratification of cardiovascular disease in end-stage liver disease is outlined, incorporating the AHA/ACC scientific statement on evaluation of cardiac disease in transplant candidates and more recent expert consensus documents. Further study is needed to clarify the ideal timing and approach for cardiovascular interventions.

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优化肝脏移植候选者的心脏状态。
综述目的:肝移植是一种被广泛接受的治疗终末期肝病的方法。随着我们对移植理解的进步,候选人年龄越来越大,心脏合并症也越来越多。心血管疾病也是移植后发病和死亡的主要原因。最新发现:术前心脏风险分层和治疗可改善肝移植术后的短期和长期预后。重要的是,监测的适当频率尚未确定。终末期肝病心脏干预的最佳时机同样不确定。总结:本文概述了终末期肝病患者心血管疾病风险分层的方法,并结合了AHA/ACC关于移植候选者心脏病评估的科学声明和最新的专家共识文件。需要进一步的研究来阐明心血管干预的理想时机和方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.10
自引率
4.50%
发文量
124
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Organ Transplantation is an indispensable resource featuring key, up-to-date and important advances in the field from around the world. Led by renowned guest editors for each section, every bimonthly issue of Current Opinion in Organ Transplantation delivers a fresh insight into topics such as stem cell transplantation, immunosuppression, tolerance induction and organ preservation and procurement. With 18 sections in total, the journal provides a convenient and thorough review of the field and will be of interest to researchers, surgeons and other healthcare professionals alike.
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