Richard Lerner and the Birth of Antibody Libraries

IF 2.3 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Israel Journal of Chemistry Pub Date : 2023-11-15 DOI:10.1002/ijch.202300151
Dennis R. Burton
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Abstract

Richard Lerner had many achievements in his outstanding career. He will perhaps be remembered most for taking the helm of Scripps Research, following the founding by and tenure of Frank Dixon, and building one of the most successful biomedical research institutes in the world. Two Nobel prizes at Scripps in the past two years and one of them a second Nobel speaks for itself. But I want to cover what many consider Richard's finest scientific achievement- the development of a whole new approach to making antibodies that has been revolutionary to many aspects of basic science and medicine. I was very fortunate to be a part of that development and I give an account here and my memories of Richard during that time.

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Richard Lerner和抗体文库的诞生
理查德·勒纳在他杰出的职业生涯中取得了许多成就。在弗兰克·迪克森(Frank Dixon)创立并任职之后,他执掌斯克里普斯研究中心(Scripps Research),并建立了世界上最成功的生物医学研究机构之一,这可能是他最令人难忘的经历。在过去的两年里,斯克里普斯学院获得了两项诺贝尔奖,其中一项是第二个诺贝尔奖。但我想说的是理查德最杰出的科学成就——他发明了一种全新的制造抗体的方法,这对基础科学和医学的许多方面都是革命性的。我很幸运能成为发展的一部分,我在这里讲述我对理查德那段时间的回忆。
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来源期刊
Israel Journal of Chemistry
Israel Journal of Chemistry 化学-化学综合
CiteScore
6.20
自引率
0.00%
发文量
62
审稿时长
6-12 weeks
期刊介绍: The fledgling State of Israel began to publish its scientific activity in 1951 under the general heading of Bulletin of the Research Council of Israel, which quickly split into sections to accommodate various fields in the growing academic community. In 1963, the Bulletin ceased publication and independent journals were born, with Section A becoming the new Israel Journal of Chemistry. The Israel Journal of Chemistry is the official journal of the Israel Chemical Society. Effective from Volume 50 (2010) it is published by Wiley-VCH. The Israel Journal of Chemistry is an international and peer-reviewed publication forum for Special Issues on timely research topics in all fields of chemistry: from biochemistry through organic and inorganic chemistry to polymer, physical and theoretical chemistry, including all interdisciplinary topics. Each topical issue is edited by one or several Guest Editors and primarily contains invited Review articles. Communications and Full Papers may be published occasionally, if they fit with the quality standards of the journal. The publication language is English and the journal is published twelve times a year.
期刊最新文献
Cover Picture: (Isr. J. Chem. 8-9/2024) Special Issue on RNA-Based Catalysts that Revolutionized the Discovery of Bioactive Peptides Hexagonal and Trigonal Quasiperiodic Tilings Breaking the Degeneracy of Sense Codons – How Far Can We Go? Cover Picture: (Isr. J. Chem. 6-7/2024)
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