{"title":"Chaetomium globosum: Spotting a scarce saprophyte in bacterial-fungal co-infection of the sinuses in a post-COVID-19 patient","authors":"Neeta Gade , Soumyabrata Nag , Kiran Kumar Prathipati , Meena Mishra , Vishal Shete","doi":"10.1016/j.mmcr.2023.100618","DOIUrl":null,"url":null,"abstract":"<div><p>Atypical fungal co-infections in post-COVID-19 patients may have been underreported due to limited diagnostic methods. We present a case of <em>Chaetomium globosum</em> sinusitis in a 55-year-old post-COVID-19 patient with pain in the left side of the face, mimicking rhino-cerebral mucormycosis.</p><p>CT-paranasal sinuses showed mucosal thickening of left paranasal sinuses, biopsy of which grew a velvety, white colony. It was confirmed as <em>Chaetomium globosum</em>. The patient responded to oral Posaconazole therapy for three months.</p><p>Prompt identification of atypical fungal agents is critical for appropriate treatment.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100618"},"PeriodicalIF":1.6000,"publicationDate":"2023-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753923000507/pdfft?md5=389a2fe5fb688e007de9ded8323e926b&pid=1-s2.0-S2211753923000507-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753923000507","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
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Abstract
Atypical fungal co-infections in post-COVID-19 patients may have been underreported due to limited diagnostic methods. We present a case of Chaetomium globosum sinusitis in a 55-year-old post-COVID-19 patient with pain in the left side of the face, mimicking rhino-cerebral mucormycosis.
CT-paranasal sinuses showed mucosal thickening of left paranasal sinuses, biopsy of which grew a velvety, white colony. It was confirmed as Chaetomium globosum. The patient responded to oral Posaconazole therapy for three months.
Prompt identification of atypical fungal agents is critical for appropriate treatment.
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