{"title":"YKL-40 as a biomarker in various inflammatory diseases: A review","authors":"Nina Blazevic, Nina Blazevic, Dunja Rogic, Stipe Pelajic, Marijana Miler, Goran Glavcic, Valentina Ratkajec, Nikolina Vrkljan, Dejan Bakula, Davor Hrabar, Tajana Pavic","doi":"10.11613/bm.2024.010502","DOIUrl":null,"url":null,"abstract":"Highlights\nYKL-40 is a biomarker for inflammatory diseases’ diagnosis and prediction\nYKL-40 concentration increases with age and has variations in healthy population\nYKL-40 is convincing in pancreatic/liver disease, arthritis, bronchitis, and sepsis\nYKL-40 is debatable in cardiovascular/neurological/renal disease, diabetes, asthma\nFuture larger studies and age-stratified reference intervals of YKL-40 are needed","PeriodicalId":9021,"journal":{"name":"Biochemia Medica","volume":"14 1","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochemia Medica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.11613/bm.2024.010502","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Highlights
YKL-40 is a biomarker for inflammatory diseases’ diagnosis and prediction
YKL-40 concentration increases with age and has variations in healthy population
YKL-40 is convincing in pancreatic/liver disease, arthritis, bronchitis, and sepsis
YKL-40 is debatable in cardiovascular/neurological/renal disease, diabetes, asthma
Future larger studies and age-stratified reference intervals of YKL-40 are needed
期刊介绍：
Biochemia Medica is the official peer-reviewed journal of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Journal provides a wide coverage of research in all aspects of clinical chemistry and laboratory medicine. Following categories fit into the scope of the Journal: general clinical chemistry, haematology and haemostasis, molecular diagnostics and endocrinology. Development, validation and verification of analytical techniques and methods applicable to clinical chemistry and laboratory medicine are welcome as well as studies dealing with laboratory organization, automation and quality control. Journal publishes on a regular basis educative preanalytical case reports (Preanalytical mysteries), articles dealing with applied biostatistics (Lessons in biostatistics) and research integrity (Research integrity corner).
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