Uroš Grošelj, Marija Gršič, Anže Meden, Damijan Knez, Marko Jukič, Jurij Svete, Stanislav Gobec
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引用次数: 0
Abstract
Synthesis and anticholinesterase activity of 18 previously unpublished indole- and tryptophan-derived compounds are disclosed. These sp3-rich compounds containing an indole structural unit exhibit selective submicromolar inhibition of human butyrylcholinesterase (hBChE). The structures of the newly synthesized compounds were confirmed by 1H and 13C NMR, IR spectroscopy, and high-resolution mass spectrometry.
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