Pharmacological and Non-Pharmacological Methods of Postoperative Pain Control Following Oral and Maxillofacial Surgery: A Systematic Review.

IF 0.9 Q3 SURGERY World Journal of Plastic Surgery Pub Date : 2023-01-01 DOI:10.52547/wjps.12.2.3
Amin Rahpeyma, Majid Eshghpour, Tooraj Vaezi, Shams Abdolrahim, Amir Manafi, Navid Manafi
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Abstract

Background: We aimed to investigate the pharmacological and non-pharmacological interventions used for mitigating pain.

Methods: We integrated randomized controlled trials (RCTs) chosen from PubMed, Google scholar, and Scopus and aimed at assessing the effectiveness of one or multiple variants of Non-steroidal anti-inflammatory drugs (NSAIDs), as well as Narcotic analgesics, compared to corticosteroids, curcumin, hyaluronic acid, and antibiotics. In addition, trials utilizing NSAIDs, including Rofecoxib, which have been withdrawn from market circulation, were deemed ineligible for inclusion.

Result: A total of 9 RCTs were evaluated in this study, and the patients' postoperative pain was assessed using the visual analog scale (VAS) and the time measurement. Moreover, there were various approaches to alleviating pain and discomfort.

Conclusion: The administration of ibuprofen prior to surgery leads to a marked reduction in pain. Pharmacological interventions, such as the administration of dexamethasone and oxycodone, alongside non-pharmacological interventions, such as laser therapy, have been shown to effectively alleviate the discomfort resulting from surgical procedures on the jaw and face.

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口腔颌面外科术后疼痛控制的药物和非药物方法:系统综述。
背景:我们旨在调查用于减轻疼痛的药物和非药物干预措施:我们旨在调查用于减轻疼痛的药物和非药物干预措施:我们整合了从 PubMed、Google scholar 和 Scopus 选取的随机对照试验 (RCT),旨在评估非甾体抗炎药 (NSAID) 的一种或多种变体以及麻醉性镇痛药与皮质类固醇、姜黄素、透明质酸和抗生素相比的有效性。此外,使用非甾体抗炎药(包括已退出市场流通的罗非昔布)的试验被认为不符合纳入条件:结果:本研究共评估了 9 项 RCT,并使用视觉模拟量表(VAS)和时间测量法评估了患者的术后疼痛。此外,还有多种缓解疼痛和不适的方法:结论:术前服用布洛芬可明显减轻疼痛。药物干预(如地塞米松和羟考酮)和非药物干预(如激光治疗)已被证明能有效减轻颌面部手术带来的不适。
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