Antibiogram Profiling of Clinical Isolates From Several Renowned Diagnostic Centers In Dhaka City, Bangladesh

Stamford Journal of Microbiology Pub Date : 2023-12-21 DOI:10.3329/sjm.v13i1.70406

R. Sultana, TJ Shorna, A. Khatun, M. Ferdous, C. Mazumder, MA Uddin

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Abstract

Antibiotic resistance is a global concern that has emerged in recent years due to inappropriate and indiscriminate use of antibiotics. It is important to follow the changes in this antibiotic resistance for the sake of better treatment and patient management. The aim of this study was to collect clinical isolates from some renowned diagnostic centers and to determine their susceptibility patterns in different age and sex groups of patients. Clinical samples from a number of patients with various infectious symptoms were selected and microbiologically analyzed. Antibiotic resistance patterns for 15 different antibiotics Amikacin, Azithromycin, Ciprofloxacin, Ceftriaxone, Cefuroxime, Erythromycin, Cefoxitin, Gentamicin, Imipenem, Linezolid, Meropenem, Norfloxacin, Piperacillin, Penicillin and Vancomycin were evaluated by the Agar-disc-diffusion method. The highest resistance of the studied pathogens to antimicrobials was seen against Azithromycin (100%) and Penicillin (100%) whereas the isolates were highly sensitive to Norfloxacin, Vancomycin, Linezolid and Cefoxitin. Stamford Journal of Microbiology, 2023. Vol. 13, Issue 1, p. 11-14

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孟加拉国达卡市几家知名诊断中心的临床菌株抗生素谱分析

抗生素耐药性是近年来由于抗生素使用不当和滥用而出现的一个全球性问题。为了更好地治疗和管理病人，跟踪抗生素耐药性的变化非常重要。本研究的目的是从一些著名的诊断中心收集临床分离物，并确定不同年龄和性别的患者对这些分离物的敏感性模式。研究选取了一些有各种感染症状的患者的临床样本，并对其进行了微生物学分析。采用琼脂盘扩散法评估了 15 种不同抗生素的耐药性模式：阿米卡星、阿奇霉素、环丙沙星、头孢曲松、头孢呋辛、红霉素、头孢西丁、庆大霉素、亚胺培南、利奈唑胺、美罗培南、诺氟沙星、哌拉西林、青霉素和万古霉素。所研究的病原体对阿奇霉素（100%）和青霉素（100%）的耐药性最高，而对诺氟沙星、万古霉素、利奈唑胺和头孢西丁高度敏感。第 13 卷第 1 期第 11-14 页

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Stamford Journal of Microbiology

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