Results of neurotrophic keratopathy treatment by direct corneal neurotization

M. Gushchina, S. Butsan, V. Sergeeva, K. Salikhov, A. V. Tereshchenko, E. Erokhina, S.A. Malkov
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Abstract

Relevance. Trigeminal nerve defeat can lead to the development of neurotrophic keratopathy. The only pathogenetically justified method of treating this pathology is corneal neurotization. Purpose. To develop rehabilitation tactic for the patients with neurotrophic keratopathy based on the analysis of the results of operations performed according to the author's technique of direct corneal neurotization. Material and methods. 10 direct corneal neurotizations: with initial manifestations – in 2 cases and in the advanced stage of neurotrophic keratopathy – in 8 cases. Results and discussion. Postoperative period proceeded without complications. Corneal sensitivity was restored in 60%. In all cases, corneal transparency improved, the density of the eyesore and the depth of the invasion of opacities decreased, subbasal nerve fibers began to be visualized, positive dynamic in the state of tear production were observed. Perforation defects of the cornea was closed. In initial stage of the disease corneal opacity has almost completely regressed. Conclusion. Direct corneal neurotization provides restoration of its sensitivity, prevention of neurotrophic keratopathy, which provides medical and social rehabilitation. Key words: facial nerve, paralytic lagophthalmos, abductive nerve, convergent paralytic strabismus, trigeminal nerve, corneal innervation, corneal opacity, corneal sensitivity, esthesiometry, supraorbital nerve, supratrochlear nerve
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通过直接角膜神经化治疗神经营养性角膜病的结果
相关性。三叉神经受损会导致神经营养性角膜病的发生。治疗这种病症的唯一病理上合理的方法是角膜神经化。目的在分析根据作者的直接角膜神经化技术进行的手术结果的基础上,为神经营养性角膜病患者制定康复策略。材料与方法10例直接角膜神经化手术:2例为初期表现,8例为神经营养性角膜病晚期。结果与讨论。术后无并发症。60%的患者恢复了角膜敏感性。在所有病例中,角膜透明度都得到了改善,翳眼密度和翳眼侵入深度都有所下降,基底膜下神经纤维开始显现,泪液分泌状态也出现了积极的动态变化。角膜的穿孔缺损被闭合。疾病初期的角膜翳几乎完全消退。结论直接角膜神经化术可恢复角膜的敏感性,预防神经营养性角膜病,从而实现医疗和社会康复。关键词:面神经、麻痹性斜视、外展神经、会聚性麻痹性斜视、三叉神经、角膜神经支配、角膜混浊、角膜敏感性、雌激素测定法、眶上神经、虹膜上神经
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